Palabras clave
Fotosensibilizadores
Oxígeno singulete
Nanopartículas
Cómo citar
Resumen
La terapia fotodinámica es una técnica alternativa para el tratamiento del cáncer y diversas enfermedades mediante luz, oxígeno molecular y un fotosensibilizador (Fs). Un Fs es una molécula especializada en absorber un fotón para estimular la promoción de un estado basal a un estado triplete excitado que, al encontrarse con oxígeno molecular, es capaz de producir especies reactivas de oxígeno. En el presente trabajo, se reporta la síntesis de un compósito nanoestructurado de nanoesferas de carbono (CNS) usado como fotosensibilizador conjugado con nanopartículas de oro (AuNPs) soportados en una matriz de quitosano-GMA (Q-GMA). Se observó por medio de las caracterizaciones de FT-IR, UV-VIS y SEM que los compósitos no alteraron la estructura de la matriz ni del plasmón característico de las AuNPs en las muestras de Q-GMA-CNS-AuNPs a 0.4 y 0.6 mM, los cuales son considerados como fotosensibilizadores potenciales para su aplicación en terapia fotodinámica.
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